Acridine Orange (Acridine Orange Hemi (Zinc Chloride) Salt) (CAS Number: 10127-02-3)

Synonym: 3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt, 3,6-Bis(dimethylamino)acridinium chloride hemi(zinc chloride salt), Basic Orange 14General description : Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels.Application : Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes. Suitable for- detection of nucleic acids separated by gel electrophoresis- fluorescence and epifluorescence microscopy- analysis of mitochondria and lysosomes by flow cytometry- DNA staining in apoptosis studiesAcridine Orange hemi (zinc chloride) salt has been used to stain primary human umbilical vein endothelial cells (HUVEC) and is used in micronucleus tests (MNTs).Biochem/physiol Actions : Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test. About the Company GST Registration Date: 2017 Legal Status of Firm: Partnership Number of Employees: Upto 10 People Annual Turnover: 5 - 25 Cr company-description: Founded in the year 1988, Innovative has continued to expand the scope of its business as a chemical trading company with a constant focus on serving science, research and technology. Our business encompasses Life Sciences, Nutraceuticals, Organic/Inorganic Chemistry and Analytical Chemistry. To be able to better serve the science community we have further divided our business under two main business divisions. · Bulk Division Under this division we import, stock and supply more than 500 chemicals in bulk and offer very competitive wholesale pricing for the same. Our product range here mainly includes Amino Acids, Buffers, Carbohydrates, Biochemicals, Nucleosides, Organic Intermediates, Inorganic Salts, Stains and Indicators. This division mainly focuses on catering to all your Manufacturing, Repackaging and Pharmaceutical needs. · Laboratory Division Under this division we partner with some of the leading global companies as their business partners / authorized distributors to supply their products. Our brands portfolio consists of Sigma-Aldrich, Alfa-Aesar, Honeywell, TCI Japan, BDH/VWR, Combi-Blocks and many more. We are also able to supply Reference Standards of USP, EP, BP, TRC and many more renowned global companies. We are having more than 1500 items available from ready stock here and can supply over a million products on forward delivery basis. This division mainly focuses on catering to all your Laboratory, R&D, Q.C., Chromatography, Diagnostic and Research needs. As a trading company, we have focused each of our divisions on a strategic area with an eye on emerging trends. Overall we remain focused on sharpening our competitive edge and shall continue to pursue various capabilities of value for all our customers. Introducing ourselves as one of leading Chemical suppliers and presenting to all our customers with our Complete Product List has been solely our pleasure. We request you to kindly favour us with your valued inquiries from both, within this Catalog and otherwise. Rest assured your interests will be our first preference and of course, when it comes to service, the INNOVATIVE experience is unparalleled. Thanking you. Nilesh Shah Tushar Shah (Partners - Innovative)