1. Chemical Identity Chemical Name: Dienogest IUPAC Name: (17α)-17-Hydroxy-3-oxo-19-nor-17-pregna-4,9-dien-21-nitrile Molecular Formula: C₂₀H₂₅NO₂ Molecular Weight: 311.42 g/mol Chemical Class: Synthetic progestogen (progestin); sex hormone CAS Number: 65928-58-7 Dienogest is a fourth-generation synthetic progestin, structurally related to 19-nortestosterone derivatives but pharmacologically distinguished by strong progestational activity with low androgenic effects. 2. Structural Characteristics Dienogest has a hybrid structure combining features of progesterone derivatives and 19-nor steroids, characterized by: Cyanomethyl (nitrile) group at C17, contributing to receptor selectivity 3-keto functional group required for progestational activity Δ4 and Δ9 double bonds in the steroid nucleus Absence of the C19 methyl group, typical of 19-nor compounds These structural features provide: High affinity for progesterone receptors Minimal androgenic activity Antiandrogenic properties in some clinical contexts 3. Physicochemical Properties Appearance: White or almost white crystalline powder Odor: Practically odorless Solubility: Practically insoluble in water Soluble in ethanol, methanol, acetone, and chloroform Melting Point: ~210-214 °C Lipophilicity: Moderate Stability: Stable under dry, cool, light-protected conditions 4. Mechanism of Action Dienogest acts as a selective progesterone receptor agonist: Suppresses gonadotropin secretion, reducing ovarian estrogen production Induces decidualization and atrophy of endometrial tissue Exhibits anti-inflammatory and anti-proliferative effects in endometrial cells Shows antiandrogenic activity due to low androgen receptor affinity These properties make dienogest particularly useful in endometriosis management and gynecological hormonal therapy. About the Company GST Registration Date: 2023 Legal Status of Firm: Limited Company Number of Employees: "},{"DATA":"2023","TITLE":"Year of Establishment"},{"DATA":"","TITLE":"Standards \u0026 Quality Certifications"},{"DATA":"Limited Company (Ltd./Pvt.Ltd.)","TITLE":"Legal Status of Firm"},{"DATA":"","TITLE":""},{"DATA":"","TITLE":"Annual Turnover"},{"DATA":"","TITLE":"GST Partner Name"},{"DATA":"2023","TITLE":"GST Registration Year"},{"DATA":"Limited Company","TITLE":"GST Legal Status of Firm"},{"DATA":"Trader - Wholesaler/Distributor","TITLE":"GST Nature of Business"},{"DATA":"1.5 - 5 Cr","TITLE":"GST Annual Turnover"},{"DATA":"Office / Sale Office,Import,Export,Retail Business,Wholesale Business,Others","TITLE":"GST Additional NOB"}],"CAT_ID":"187","CITY":"Vadodara","CITY_ID":"70491","COMPANYNAME":"Suktas Organic And Lifescience Private Limited","COMPANY_VIDEO_LINK":"","CTA_DOC_PATH":"","DELIVERY_TIME":"3 weeks","DISCLAIMER_KEY":1,"DISCLAIMER_TEXT":["Verification of drug license 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Chemical Identity \n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Name:\u003c/b\u003e Dienogest\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eIUPAC Name:\u003c/b\u003e (17\u0026alpha;)-17-Hydroxy-3-oxo-19-nor-17-pregna-4,9-dien-21-nitrile\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Formula:\u003c/b\u003e C₂₀H₂₅NO₂\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eMolecular Weight:\u003c/b\u003e 311.42 g/mol\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eChemical Class:\u003c/b\u003e Synthetic progestogen (progestin); \u003cb\u003esex hormone\u003c/b\u003e\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCAS Number:\u003c/b\u003e 65928-58-7\u003c/p\u003e\n\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003eDienogest is a \u003cb\u003efourth-generation synthetic progestin\u003c/b\u003e, structurally related to 19-nortestosterone derivatives but pharmacologically distinguished by \u003cb\u003estrong progestational activity with low androgenic effects\u003c/b\u003e.\u003c/p\u003e\n2. Structural Characteristics\n\u003cp\u003eDienogest has a \u003cb\u003ehybrid structure\u003c/b\u003e combining features of progesterone derivatives and 19-nor steroids, characterized by:\u003c/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003eCyanomethyl (nitrile) group at C17\u003c/b\u003e, contributing to receptor selectivity\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003e3-keto functional group\u003c/b\u003e required for progestational activity\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cb\u003e\u0026Delta;4 and \u0026Delta;9 double bonds\u003c/b\u003e in the steroid nucleus\u003c/p\u003e\n\u003c/li\u003e\n\u003cli\u003e\n\u003cp\u003eAbsence of the \u003cb\u003eC19 methyl group\u003c/b\u003e, typ...
