Hydroxypropyl Methylcellulose Phthalate, 25Kg

PRODUCT : HYPROMELLOSE PHTHALATE Hypromellose Phthalate also known as HPMC-P or Hydroxy Propyl Methyl Cellulose Phthalate or Cellulose,2-hydroxypropyl methyl ether, phthalic acid Ester. CAS NO (9050-31-1) STRUCTURE: SPECIFICATION: Test HP-55 HP-55S HP-50 Dissolving pH Starts @ 5.5 Starts @ 5.5 Starts @5.0 Labelled Viscosity@20C 40 cst 170 cst 55 cst Viscosity in cst@20C 32cst-48cst 136cst - 204 cst 44cst - 66cst Nominal Phthalyl content 31% 31% 24% Phthalyl content 27.0% - 35.0% 27.0% - 35.0% 21.0% - 27.0 % Description & Solubility Conforms Conforms Conforms Identification Conforms Conforms Conforms Water content NMT 5.0% NMT 5.0% NMT 5.0% Sulphated Ash NMT 0.20% NMT 0.20% NMT 0.20% Chloride NMT0.07% NMT0.07% NMT0.07% Heavy Metals NMT 0.001% NMT 0.001% NMT 0.001% Free Phthalic Acid NMT 1.0% NMT 1.0% NMT 1.0% PROPERTIES: HPMC-P i.e. Hypromellose Phthalate has higher moisture barrier property. Thus less prone to hydrolysis due to humidity. Different grades are available to correlate required pH dissolution in Intestine i.e. from pH 5.0 to pH 5.5. This is achieved by controlled Variation in phthalyl content. Two types of pH variations in solubilities are available. HP-55, HP-55S & HP-50. Selection of required Grade of HPMC-P is made according to the requirements of formulations. Grade HP-55S is a special type of HP-55 having difference in molecular Weight and higher simulated gastric fluid resistance and viscosity. HP-55 is well recognized and applied as a general enteric coating agent, is well accepted in pharma industries. HP-55S, due to its higher molecular weight and higher degree of Polymerization w.r.t. HP-55, has higher viscosity, higher mechanical Strength of film and higher resistance to simulated gastric fluid of coated Formulation.This gives less percentage use in coating for tablets,gives better Strength to fragile tablets or granules or pellets. HP-50, can be used to dissolve the tablets at lower pH in duodenam (pH 5.0), first part of the small intestine. All the grades are available in BP/USPNF/EP. It can also be made and Supplied as per other recognized pharmacopeia. APPLICATIONS: - Film coating of tablets,capsules and pellets - Enteric coating of tablets,pellets and capsules - Sustained release formulations - Delayed release formulations - Pellet coating of medical formulation - Taste masking of the tablets ADVANTAGES OF FILM COATING: - Soothens pelletibility by masking odor and smell. - Easy to swallow. - Enhances product appearance. - Protection of formulations from air oxidation,moisture and light. - Improves efficacy of the drug. - Prevents gastric cell irritation due to drugs. - Drug will not get destroyed due to acidic pH of the stomach, thus better medical treatment to the patients. About the Company GST Registration Date: 2020 Legal Status of Firm: Proprietorship Number of Employees: 11 To 25 People Annual Turnover: 0 - 40 L company-description: Inaugurated in the year 2010 at SURAT,Gujarat (India), we "ASPIRE HEALTHCARE" are a Proprietor firm that is engaged in manufacturing, trading and supplying a wide range Anti Malarial Injection, Anti Infective Tablet And Injection, Gastroenterology Capsule, Womens Health Tablet, Analgesic And Anti Inflammatory Tablet, etc. The medicines provided by us are processed using the best grade chemical compounds and latest processing techniques under the meticulous supervision of our experienced professionals in tandem with set medical norms and standards. As per the set medical standards, the medicines provided by us are highly recognized among our renowned customers for their salient features like quick result, precise composition, enhanced shelf life, zero side effects, high purity and safe consumption. In addition to this, we provide these medicines in various packaging options as per the variegated needs of clients at rock bottom prices.