Dextromethorphan HBr (Hydrobromide) is a commonly used antitussive (cough suppressant) that is available in various formulations, including powder form for pharmaceutical use. Dextromethorphan is widely used in over-the-counter (OTC) cough and cold medications. When it is in its hydrobromide form, it is often utilized in preparations that are meant to be mixed into solutions or other oral dosage forms. Here's a detailed description of Dextromethorphan HBr Powder: 1. Chemical Description: Chemical Name: Dextromethorphan Hydrobromide Molecular Formula: C18H25NO·HBr Molecular Weight: 370.31 g/mol CAS Number: 125-71-3 (Dextromethorphan Hydrobromide) Synonyms: Dextromethorphan HBr, Dextromethorphan Hydrobromide Dextromethorphan HBr is a synthetic derivative of morphine but is not addictive or habit-forming at therapeutic doses. It works by affecting the brain's cough center, suppressing the urge to cough without causing sedation or respiratory depression at usual doses. 3. Uses and Indications: Cough Suppressant: Dextromethorphan is primarily used to suppress coughing associated with common colds, bronchitis, or other respiratory conditions where coughing is present but not productive. Relief of Dry Cough: It is effective for treating dry, non-productive coughs that do not produce mucus or phlegm. Over-the-counter medications: Dextromethorphan is included in many OTC cough syrups, lozenges, and tablets. The powdered form of Dextromethorphan HBr may be used as an intermediate in the manufacture of these finished pharmaceutical products, or it can be used directly for patients requiring precise dosage formulations in clinical settings. 4. Physical Characteristics: Appearance: Dextromethorphan HBr powder is typically a white to off-white crystalline powder. Solubility: It is soluble in water and alcohol, which makes it easy to incorporate into liquid or syrup formulations. Odor: The powder is odorless or may have a faint, characteristic smell. 5. Purity: Pharmaceutical-grade Dextromethorphan HBr powder typically has a purity of 98% or higher. It is essential for the powder to meet stringent quality control standards to ensure that the correct dose is delivered in the final formulation. 6. Dosage and Strength: Dextromethorphan HBr powder is often used in the preparation of oral dosage forms, such as syrups, tablets, or capsules. The specific dosage will depend on the final formulation and the intended use. Typical oral dosages for adults are: 10-20 mg every 4-6 hours as needed. Maximum daily dose typically 120 mg (for adults). Children's dosages depend on age, and the drug should be administered according to medical guidance to avoid potential overuse, which can lead to serious side effects. 7. Side Effects: Although Dextromethorphan HBr is generally well tolerated, it may cause side effects, especially if taken in excess or in combination with other substances. Common side effects include: Drowsiness or dizziness Nausea Vomiting Stomach discomfort Severe side effects (more common with abuse or misuse): Hallucinations (due to higher doses) Elevated heart rate or high blood pressure Respiratory distress (with excessive doses) Severe sedation (especially if combined with alcohol or other central nervous system depressants) About the Company GST Registration Date: 2017 Legal Status of Firm: Partnership Number of Employees: Upto 10 People Annual Turnover: 25 - 100 Cr company-description: We, Shreeji Pharma International an ISO 9001:2008 certified company, established in 2004, are proud to introduce ourselves as one of the leading Merchants exporters and global sourcing company in India in the field of Active Pharma Ingredients, Chemicals, Pharmaceuticals Raw Materials, Nutraceuticals, Herbals, Phytochemicals & Intermediates. 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